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PD-L1: PD-1 Interaction Contributes to the Functional Suppression of T-Cell Responses to Human Uveal Melanoma Cells In Vitro

PURPOSE: To assess the expression of PD-L1 on human uveal melanomas and its potential to suppress T-cell function. METHODS: A panel of primary and metastatic uveal melanoma cell lines was evaluated for PD-L1 expression by RT-PCR and flow cytometric analysis. Uveal melanoma-containing eyes were exami...

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Détails bibliographiques
Auteurs principaux: Yang, Wanhua, Chen, Peter W., Li, Haochuan, Alizadeh, Hassan, Niederkorn, Jerry Y.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465808/
https://ncbi.nlm.nih.gov/pubmed/18296654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1606
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