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Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor
UL18 is a human cytomegalovirus class I MHC (MHCI) homolog that binds the host inhibitory receptor LIR-1 and the only known viral MHC homolog that presents peptides. The 2.2-Å structure of a LIR-1/UL18/peptide complex reveals increased contacts and optimal surface complementarity in the LIR-1/UL18 i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2465803/ https://ncbi.nlm.nih.gov/pubmed/18632577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804551105 |
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