Llwytho...

Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules

To understand the functions of SPG6, mutated in the neurodegenerative disease hereditary spastic paraplegia, and of ichthyin, mutated in autosomal recessive congenital ichthyosis, we have studied their Drosophila ortholog, spichthyin (Spict). Spict is found on early endosomes. Loss of Spict leads to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Xinnan, Shaw, W. Robert, Tsang, Hilda T. H., Reid, Evan, O'Kane, Cahir J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464677/
https://ncbi.nlm.nih.gov/pubmed/17220882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1841
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