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Mechanism of protein remodeling by ClpA chaperone

ClpA, a newly discovered ATP-dependent molecular chaperone, remodels bacteriophage P1 RepA dimers into monomers, thereby activating the latent specific DNA binding activity of RepA. We investigated the mechanism of the chaperone activity of ClpA by dissociating the reaction into several steps and de...

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Bibliografiske detaljer
Main Authors: Pak, Marie, Wickner, Sue
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24603/
https://ncbi.nlm.nih.gov/pubmed/9144162
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