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Identification of Tumor-initiating Cells in a p53 Null Mouse Model of Breast Cancer
Using a syngeneic p53 null mouse mammary gland tumor model that closely mimics human breast cancer, we have identified by limiting dilution transplantation as well as in vitro mammosphere assay a Lin(−)CD29(H)CD24(H) subpopulation of tumor-initiating cells. Upon subsequent transplantation, this subp...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2459340/ https://ncbi.nlm.nih.gov/pubmed/18559513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6353 |
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