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Intratumoral heterogeneity in a p53 null mouse model of human breast cancer

Intratumoral heterogeneity correlates with clinical outcome and reflects the cellular complexity and dynamics within a tumor. Such heterogeneity is thought to contribute to radio- and chemoresistance since many treatments may only target certain tumor cell subpopulations. A better understanding of t...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Zhang, Mei, Tsimelzon, Anna, Chang, Chi-Hsuan, Fan, Cheng, Wolff, Andrew, Perou, Charles M., Hilsenbeck, Susan G., Rosen, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420701/
https://ncbi.nlm.nih.gov/pubmed/25735774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-1101
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