Electrophilic Cyclopentenone Neuroprostanes Are Anti-inflammatory Mediators Formed from the Peroxidation of the ω-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid

The ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) possesses potent anti-inflammatory properties and has shown therapeutic benefit in numerous inflammatory diseases. However, the molecular mechanisms of these anti-inflammatory properties are poorly understood. DHA is highly susceptible to...

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Main Authors: Musiek, Erik S., Brooks, Joshua D., Joo, Myungsoo, Brunoldi, Enrico, Porta, Alessio, Zanoni, Giuseppe, Vidari, Giovanni, Blackwell, Timothy S., Montine, Thomas J., Milne, Ginger L., McLaughlin, BethAnn, Morrow, Jason D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459280/
https://ncbi.nlm.nih.gov/pubmed/18490445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803625200
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