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Termination of Ca(2+) release by a local inactivation of ryanodine receptors in cardiac myocytes

In heart, a robust regulatory mechanism is required to counteract the regenerative Ca(2+)-induced Ca(2+) release from the sarcoplasmic reticulum. Several mechanisms, including inactivation, adaptation, and stochastic closing of ryanodine receptors (RyRs) have been proposed, but no conclusive evidenc...

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Hlavní autoři: Sham, James S. K., Song, Long-Sheng, Chen, Ye, Deng, Li-Hua, Stern, Michael D., Lakatta, Edward G., Cheng, Heping
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24581/
https://ncbi.nlm.nih.gov/pubmed/9844021
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