Direct measurement of SR release flux by tracking ‘Ca(2+) spikes’ in rat cardiac myocytes

1. Ca(2+) release flux across the sarcoplasmic reticulum (SR) during cardiac excitation-contraction coupling was investigated using a novel fluorescence method. Under whole-cell voltage-clamp conditions, rat ventricular myocytes were dialysed with a high concentration of EGTA (4.0 mm, 150 nm free Ca...

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Detalhes bibliográficos
Main Authors: Song, Long-Sheng, Sham, James S K, Stern, Michael D, Lakatta, Edward G, Cheng, Heping
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231234/
https://ncbi.nlm.nih.gov/pubmed/9769413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.677bd.x
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