Phenotypic switching in the human pathogenic fungus Cryptococcus neoformans is associated with changes in virulence and pulmonary inflammatory response in rodents

High-frequency reversible changes in colony morphology were observed in three strains of Cryptococcus neoformans. For one strain (SB4, serotype A), this process produced three colony types: smooth (S), wrinkled (W), and serrated (C). The frequency of switching between colony types varied for the ind...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Goldman, David L., Fries, Bettina C., Franzot, Sarah P., Montella, Lya, Casadevall, Arturo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24559/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9843999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.25.14967
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