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Phenotypic switching in the human pathogenic fungus Cryptococcus neoformans is associated with changes in virulence and pulmonary inflammatory response in rodents

High-frequency reversible changes in colony morphology were observed in three strains of Cryptococcus neoformans. For one strain (SB4, serotype A), this process produced three colony types: smooth (S), wrinkled (W), and serrated (C). The frequency of switching between colony types varied for the ind...

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Библиографические подробности
Главные авторы: Goldman, David L., Fries, Bettina C., Franzot, Sarah P., Montella, Lya, Casadevall, Arturo
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC24559/
https://ncbi.nlm.nih.gov/pubmed/9843999
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