In vitro demonstration of transport and delivery of antibiotics by polymorphonuclear leukocytes.

Several antibiotics are concentrated inside polymorphonuclear leukocytes (PMN). To investigate whether PMN could act as vehicles for delivery of antibiotics, we combined an assay measuring PMN chemotaxis under agarose with a bioassay measuring levels of antibiotic in agar. Double-layer plates were m...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Frank, M O, Sullivan, G W, Carper, H T, Mandell, G L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2584
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