In vitro demonstration of transport and delivery of antibiotics by polymorphonuclear leukocytes.

Several antibiotics are concentrated inside polymorphonuclear leukocytes (PMN). To investigate whether PMN could act as vehicles for delivery of antibiotics, we combined an assay measuring PMN chemotaxis under agarose with a bioassay measuring levels of antibiotic in agar. Double-layer plates were m...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Frank, M O, Sullivan, G W, Carper, H T, Mandell, G L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2584
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