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In vitro demonstration of transport and delivery of antibiotics by polymorphonuclear leukocytes.

Several antibiotics are concentrated inside polymorphonuclear leukocytes (PMN). To investigate whether PMN could act as vehicles for delivery of antibiotics, we combined an assay measuring PMN chemotaxis under agarose with a bioassay measuring levels of antibiotic in agar. Double-layer plates were m...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Frank, M O, Sullivan, G W, Carper, H T, Mandell, G L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245511/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2584
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