In vitro demonstration of transport and delivery of antibiotics by polymorphonuclear leukocytes.

Several antibiotics are concentrated inside polymorphonuclear leukocytes (PMN). To investigate whether PMN could act as vehicles for delivery of antibiotics, we combined an assay measuring PMN chemotaxis under agarose with a bioassay measuring levels of antibiotic in agar. Double-layer plates were m...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Frank, M O, Sullivan, G W, Carper, H T, Mandell, G L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2584
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