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The ability of suramin to block CD4-gp120 binding is reversed in the presence of albumin.

We have shown that suramin can directly inhibit the binding of the human immunodeficiency virus type 1 gp120 envelope protein to immobilized CD4, thus helping to explain the previously described antiviral properties of suramin. However, physiological concentrations of serum albumin significantly att...

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Bibliografske podrobnosti
Main Authors: Yao, X J, Wainberg, M A, Richard, M, Pollak, M
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC245445/
https://ncbi.nlm.nih.gov/pubmed/1810199
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