Pharmacokinetics and tissue penetration of a single 1,000-milligram, intravenous dose of metronidazole for antibiotic prophylaxis of colorectal surgery.

The levels of metronidazole in serum and tissue penetration of metronidazole were studied after prophylactic administration in 11 patients undergoing elective colorectal surgery. A single dose of 1,000 mg given intravenously was administered before surgery. Adequate drug levels in serum (greater tha...

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Detalhes bibliográficos
Main Authors: Martin, C, Sastre, B, Mallet, M N, Bruguerolle, B, Brun, J P, De Micco, P, Gouin, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC245438/
https://ncbi.nlm.nih.gov/pubmed/1810194
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