Pharmacokinetics and tissue penetration of single-dose cefotetan used for antimicrobial prophylaxis in patients undergoing colorectal surgery.

The pharmacokinetics and tissue penetration of cefotetan were studied after a single injection of 2 g given intravenously for antimicrobial prophylaxis to 16 consecutive patients undergoing colorectal surgery. Concentrations in tissue greater than or equal to the MIC for 90% of the main pathogens te...

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Bibliographic Details
Main Authors: Martin, C, Portet, C, Lambert, D, Bruguerolle, B, Sastre, B, De Micco, P, Gouin, F
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC188845/
https://ncbi.nlm.nih.gov/pubmed/1510402
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