Pharmacokinetics and tissue penetration of single-dose cefotetan used for antimicrobial prophylaxis in patients undergoing colorectal surgery.

The pharmacokinetics and tissue penetration of cefotetan were studied after a single injection of 2 g given intravenously for antimicrobial prophylaxis to 16 consecutive patients undergoing colorectal surgery. Concentrations in tissue greater than or equal to the MIC for 90% of the main pathogens te...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Martin, C, Portet, C, Lambert, D, Bruguerolle, B, Sastre, B, De Micco, P, Gouin, F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188845/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.1115
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