In vivo evaluation of NM441, a new thiazeto-quinoline derivative.
NM441 is a lipophilic prodrug of a new thiazeto-quinoline carboxylic acid derivative NM394, and when it is administered orally it is readily absorbed and hydrolyzed to its parent compound. After oral administration of NM441 at a dose of 20 mg/kg to dogs, the peak concentration of NM394 in plasma was...
Kaydedildi:
| Yayımlandı: | Antimicrob Agents Chemother |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1991
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245419/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1667252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.12.2496 |
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