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Atomic level computational identification of ligand migration pathways between solvent and binding site in myoglobin

Myoglobin is a globular protein involved in oxygen storage and transport. No consensus yet exists on the atomic level mechanism by which oxygen and other small nonpolar ligands move between the myoglobin's buried heme, which is the ligand binding site, and surrounding solvent. This study uses r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ruscio, Jory Z., Kumar, Deept, Shukla, Maulik, Prisant, Michael G., Murali, T. M., Onufriev, Alexey V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453746/
https://ncbi.nlm.nih.gov/pubmed/18599444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710825105
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