Role of hybrid tRNA-binding states in ribosomal translocation

During translation, tRNAs must move rapidly to their adjacent sites in the ribosome while maintaining precise pairing with mRNA. This movement (translocation) occurs in a stepwise manner with hybrid-state intermediates, but it is unclear how these hybrid states relate to kinetically defined events o...

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Bibliographic Details
Main Authors: Walker, Sarah E., Shoji, Shinichiro, Pan, Dongli, Cooperman, Barry S., Fredrick, Kurt
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453706/
https://ncbi.nlm.nih.gov/pubmed/18591673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710146105
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