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Hyperglycemia-Induced Reactive Oxygen Species Toxicity to Endothelial Cells Is Dependent on Paracrine Mediators

OBJECTIVE—This study determined the effects of high glucose exposure and cytokine treatment on generation of reactive oxygen species (ROS) and activation of inflammatory and apoptotic pathways in human retinal endothelial cells (HRECs). RESEARCH DESIGN AND METHODS—Glucose consumption of HRECs, human...

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Detalhes bibliográficos
Main Authors: Busik, Julia V., Mohr, Susanne, Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453610/
https://ncbi.nlm.nih.gov/pubmed/18420487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1520
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