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Hyperglycemia-Induced Reactive Oxygen Species Toxicity to Endothelial Cells Is Dependent on Paracrine Mediators

OBJECTIVE—This study determined the effects of high glucose exposure and cytokine treatment on generation of reactive oxygen species (ROS) and activation of inflammatory and apoptotic pathways in human retinal endothelial cells (HRECs). RESEARCH DESIGN AND METHODS—Glucose consumption of HRECs, human...

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Main Authors: Busik, Julia V., Mohr, Susanne, Grant, Maria B.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453610/
https://ncbi.nlm.nih.gov/pubmed/18420487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1520
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