Single daily dosing of antibiotics: importance of in vitro killing rate, serum half-life, and protein binding.

The relative importance of pharmacokinetic and pharmacodynamic parameters for the feasibility of a single daily dose (SDD) of antibiotics remains to be established. Therefore, we studied the relationship between in vitro bacteriological parameters (MIC, MBC, and killing rate [KR], defined as the red...

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Main Authors: Potel, G, Chau, N P, Pangon, B, Fantin, B, Vallois, J M, Faurisson, F, Carbon, C
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC245330/
https://ncbi.nlm.nih.gov/pubmed/1759831
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