Single daily dosing of antibiotics: importance of in vitro killing rate, serum half-life, and protein binding.
The relative importance of pharmacokinetic and pharmacodynamic parameters for the feasibility of a single daily dose (SDD) of antibiotics remains to be established. Therefore, we studied the relationship between in vitro bacteriological parameters (MIC, MBC, and killing rate [KR], defined as the red...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1759831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.10.2085 |
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