Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma

Dysregulation of growth factors and their receptors is central to human hepatocellular carcinoma (HCC). We previously demonstrated that the Frizzled-7 membrane receptor mediating the Wnt signalling can activate the β-catenin pathway and promotes malignancy in human hepatitis B virus-related HCCs. Ex...

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Autori principali: Bengochea, A, de Souza, M M, Lefrançois, L, Le Roux, E, Galy, O, Chemin, I, Kim, M, Wands, J R, Trepo, C, Hainaut, P, Scoazec, J-Y, Vitvitski, L, Merle, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453022/
https://ncbi.nlm.nih.gov/pubmed/18577996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604422
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