Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa

Aberrant CpG island (CGI) methylation occurs early in colorectal neoplasia. Quantitative methylation-specific PCR profiling applied to biopsies was used to quantify low levels of CGI methylation of 18 genes in the morphologically normal colonic mucosa of neoplasia-free subjects, adenomatous polyp pa...

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Bibliografische gegevens
Hoofdauteurs: Belshaw, N J, Elliott, G O, Foxall, R J, Dainty, J R, Pal, N, Coupe, A, Garg, D, Bradburn, D M, Mathers, J C, Johnson, I T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2008
Onderwerpen:
Molecular Diagnostics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453007/
https://ncbi.nlm.nih.gov/pubmed/18542073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604432
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