Evaluation of SQ 34,514: pharmacokinetics and efficacy in experimental herpesvirus infections in mice.

The new antiviral nucleoside SQ 34,514 [(1R-1 alpha, 2 beta, 3 alpha)-2-amino-9- [2,3-bis(hydroxymethyl)cyclobutyl]-6H-purin-6-one], the active R isomer of racemic SQ 33,054 (cyclobut-G), was evaluated for efficacy in the treatment of herpesvirus infections in mice. SQ 34,514 was orally efficacious...

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Detalhes bibliográficos
Main Authors: Braitman, A, Swerdel, M R, Olsen, S J, Tuomari, A V, Lynch, J S, Blue, B, Michalik, T, Field, A K, Bonner, D P, Clark, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC245191/
https://ncbi.nlm.nih.gov/pubmed/1656863
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