In vitro and in vivo potentiation of chloroquine against malaria parasites by an enantiomer of amlodipine.

A combination of chloroquine and amlodipine, a derivative of 1,4-dihydropyridine calcium channel blocker, was tested against Plasmodium falciparum in vitro and P. yoelii in mice. The dextrorotary enantiomer of amlodipine, practically devoid of calcium channel blocking action, increased chloroquine a...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Deloron, P, Basco, L K, Dubois, B, Gaudin, C, Clavier, F, Le Bras, J, Verdier, F
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1991
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1834011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1338
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