Chronic ethanol intake modulates vascular levels of endothelin-1 receptor and enhances the pressor response to endothelin-1 in anaesthetized rats

BACKGROUND AND PURPOSE: The contribution of endothelin-1 (ET-1) to vascular hyper-reactivity associated with chronic ethanol intake, a major risk factor in several cardiovascular diseases, remains to be investigated. EXPERIMENTAL APPROACH: The biphasic haemodynamic responses to ET-1 (0.01–0.1 nmol k...

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Main Authors: Tirapelli, C R, Legros, E, Brochu, I, Honoré, J-C, Lanchote, V L, Uyemura, S A, de Oliveira, A M, D'Orléans-Juste, P
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2451036/
https://ncbi.nlm.nih.gov/pubmed/18469849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.157
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