Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rats.

Concentrations of 3'-fluoro-3'-deoxythymidine (FDT) and 3'-deoxy-2',3'-didehydrothymidine (D4T) in plasma declined in a biexponential fashion. Total clearance of D4T (1.75 +/- 0.22 liters/h/kg; mean +/- standard deviation) was significantly greater than that of FDT (1.19 +/- 0.19 liters/h/kg) owing...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Boudinot, F D, Smith, S G, Funderburg, E D, Schinazi, R F
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1648888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.4.747
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!