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Activities of two new teicoplanin amide derivatives (MDL 62211 and MDL 62873) compared with activities of teicoplanin and vancomycin against 800 recent staphylococcal isolates from France and the United States.

MDL 62211 is the amide derivative of the teicoplanin complex and MDL 62873 is a more focused amide derivative of the teicoplanin A2-2 peak. Each investigational compound had nearly identical activity and was 2- to 16-fold more active than teicoplanin or vancomycin. The MDL 62873 MICs for 90% of the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Jones, R N, Goldstein, F W, Zhou, X Y
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245056/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1828137/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.3.584
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