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Inhibition of Plasmodium falciparum dihydropteroate synthetase and growth in vitro by sulfa drugs.

The Michaelis-Menten inhibitory constants (Kis) and the concentrations required for 50% inhibition of the Plasmodium falciparum dihydropteroate synthetase were determined for six sulfa drugs. These drugs inhibited the in vitro growth of P. falciparum (50% lethal concentration) at concentrations of 3...

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Détails bibliographiques
Auteurs principaux: Zhang, Y, Meshnick, S R
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC244989/
https://ncbi.nlm.nih.gov/pubmed/2024960
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