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W-1 solubilization and kinetics of inhibition by cilofungin of Candida albicans (1,3)-beta-D-glucan synthase.

(1,3)-beta-D-Glucan synthase of Candida albicans was rendered soluble by treatment of membrane preparations with the polyoxyethylene ether detergent W-1. Extraction with 0.025% W-1 at 4 degrees C for 24 h effectively solubilized and activated the enzyme. Under these conditions, greater than 85% of t...

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Hlavní autoři: Tang, J, Parr, T R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC244948/
https://ncbi.nlm.nih.gov/pubmed/1826595
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