W-1 solubilization and kinetics of inhibition by cilofungin of Candida albicans (1,3)-beta-D-glucan synthase.

(1,3)-beta-D-Glucan synthase of Candida albicans was rendered soluble by treatment of membrane preparations with the polyoxyethylene ether detergent W-1. Extraction with 0.025% W-1 at 4 degrees C for 24 h effectively solubilized and activated the enzyme. Under these conditions, greater than 85% of t...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Tang, J, Parr, T R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC244948/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1826595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.1.99
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