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Cilofungin (LY121019) inhibits Candida albicans (1-3)-beta-D-glucan synthase activity.

Cilofungin (LY121019) inhibited Candida albicans growth and activity of (1-3)-beta-glucan synthase, for which it was a noncompetitive inhibitor with a Ki-app of 2.5 microM. Cilofungin had no effect on chitin synthase activity. Based on these and other data, it seems likely that cilofungin inhibits f...

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Detalhes bibliográficos
Main Authors: Taft, C S, Stark, T, Selitrennikoff, C P
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC176043/
https://ncbi.nlm.nih.gov/pubmed/2977537
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