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Cilofungin (LY121019) inhibits Candida albicans (1-3)-beta-D-glucan synthase activity.

Cilofungin (LY121019) inhibited Candida albicans growth and activity of (1-3)-beta-glucan synthase, for which it was a noncompetitive inhibitor with a Ki-app of 2.5 microM. Cilofungin had no effect on chitin synthase activity. Based on these and other data, it seems likely that cilofungin inhibits f...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Taft, C S, Stark, T, Selitrennikoff, C P
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2977537/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.12.1901
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