Cilofungin (LY121019) inhibits Candida albicans (1-3)-beta-D-glucan synthase activity.

Cilofungin (LY121019) inhibited Candida albicans growth and activity of (1-3)-beta-glucan synthase, for which it was a noncompetitive inhibitor with a Ki-app of 2.5 microM. Cilofungin had no effect on chitin synthase activity. Based on these and other data, it seems likely that cilofungin inhibits f...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Taft, C S, Stark, T, Selitrennikoff, C P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2977537/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.12.1901
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