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The FACT Spt16 “peptidase” domain is a histone H3–H4 binding module
The FACT complex is a conserved cofactor for RNA polymerase II elongation through nucleosomes. FACT bears histone chaperone activity and contributes to chromatin integrity. However, the molecular mechanisms behind FACT function remain elusive. Here we report biochemical, structural, and mutational a...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2449335/ https://ncbi.nlm.nih.gov/pubmed/18579787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712293105 |
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