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Transcriptional targets of sirtuins in the coordination of mammalian physiology
Sirtuins compose a family of NAD(+)-dependent deacetylases and/or ADP-ribosyltransferases, which have been implicated in aging, metabolism and tolerance to oxidative stress. Many of the biological processes regulated by sirtuins result from the adaptation of complex gene-expression programs to the e...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447870/ https://ncbi.nlm.nih.gov/pubmed/18468877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.03.012 |
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