Identification of FRA1 and FRA2 as Genes Involved in Regulating the Yeast Iron Regulon in Response to Decreased Mitochondrial Iron-Sulfur Cluster Synthesis

The nature of the connection between mitochondrial Fe-S cluster synthesis and the iron-sensitive transcription factor Aft1 in regulating the expression of the iron transport system in Saccharomyces cerevisiae is not known. Using a genetic screen, we identified two novel cytosolic proteins, Fra1 and...

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Détails bibliographiques
Auteurs principaux: Kumánovics, Attila, Chen, Opal S., Li, Liangtao, Bagley, Dustin, Adkins, Erika M., Lin, Huilan, Dingra, Nin N., Outten, Caryn E., Keller, Greg, Winge, Dennis, Ward, Diane M., Kaplan, Jerry
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Mechanisms of Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447656/
https://ncbi.nlm.nih.gov/pubmed/18281282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801160200
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