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Yap5 Is an Iron-Responsive Transcriptional Activator That Regulates Vacuolar Iron Storage in Yeast

The transporter Ccc1 imports iron into the vacuole, which is the major site of iron storage in fungi and plants. CCC1 mRNA is destabilized under low-iron conditions by the binding of Cth1 and Cth2 to the 3′ untranslated region (S. Puig, E. Askeland, and D. J. Thiele, Cell 120:99-110, 2005). Here, we...

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Detalhes bibliográficos
Main Authors: Li, Liangtao, Bagley, Dustin, Ward, Diane M., Kaplan, Jerry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258748/
https://ncbi.nlm.nih.gov/pubmed/18070921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01219-07
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