Danaparoid sodium inhibits systemic inflammation and prevents endotoxin-induced acute lung injury in rats

INTRODUCTION: Systemic inflammatory mediators, including high mobility group box 1 (HMGB1), play an important role in the development of sepsis. Anticoagulants, such as danaparoid sodium (DA), may be able to inhibit sepsis-induced inflammation, but the mechanism of action is not well understood. We...

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Main Authors: Hagiwara, Satoshi, Iwasaka, Hideo, Hidaka, Seigo, Hishiyama, Sohei, Noguchi, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447588/
https://ncbi.nlm.nih.gov/pubmed/18380908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6851
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