Regulation of β-Catenin by a Novel Nongenomic Action of Thyroid Hormone β Receptor

We previously created a knock-in mutant mouse harboring a dominantly negative mutant thyroid hormone receptor β (TRβ(PV/PV) mouse) that spontaneously develops a follicular thyroid carcinoma similar to human thyroid cancer. We found that β-catenin, which plays a critical role in oncogenesis, was high...

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Bibliographic Details
Main Authors: Guigon, Celine J., Zhao, Li, Lu, Changxue, Willingham, Mark C., Cheng, Sheue-yann
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447128/
https://ncbi.nlm.nih.gov/pubmed/18474620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02192-07
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