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Role of the Saccharomyces cerevisiae Rad53 Checkpoint Kinase in Signaling Double-Strand Breaks during the Meiotic Cell Cycle

DNA double-strand breaks (DSBs) can arise at unpredictable locations after DNA damage or in a programmed manner during meiosis. DNA damage checkpoint response to accidental DSBs during mitosis requires the Rad53 effector kinase, whereas the meiosis-specific Mek1 kinase, together with Red1 and Hop1,...

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Bibliografische gegevens
Hoofdauteurs: Cartagena-Lirola, Hugo, Guerini, Ilaria, Manfrini, Nicola, Lucchini, Giovanna, Longhese, Maria Pia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447123/
https://ncbi.nlm.nih.gov/pubmed/18505828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00375-08
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