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MKP-1 mRNA Stabilization and Translational Control by RNA-Binding Proteins HuR and NF90

The mitogen-activated protein (MAP) kinase phosphatase 1 (MKP-1) plays a major role in dephosphorylating and thereby inactivating the MAP kinases extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38. Here, we examine the posttranscriptional events underlying the robust...

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Detalhes bibliográficos
Main Authors: Kuwano, Yuki, Kim, Hyeon Ho, Abdelmohsen, Kotb, Pullmann, Rudolf, Martindale, Jennifer L., Yang, Xiaoling, Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447119/
https://ncbi.nlm.nih.gov/pubmed/18490444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00165-08
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