Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II

The antibody response to the envelope (E) glycoprotein of dengue virus (DENV) is known to play a critical role in both protection from and enhancement of disease, especially after primary infection. However, the relative amounts of homologous and heterologous anti-E antibodies and their epitopes rem...

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Detalhes bibliográficos
Main Authors: Lai, Chih-Yun, Tsai, Wen-Yang, Lin, Su-Ru, Kao, Chuan-Liang, Hu, Hsien-Ping, King, Chwan-Chuen, Wu, Han-Chung, Chang, Gwong-Jen, Wang, Wei-Kung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447043/
https://ncbi.nlm.nih.gov/pubmed/18448542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00316-08
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