Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II

The antibody response to the envelope (E) glycoprotein of dengue virus (DENV) is known to play a critical role in both protection from and enhancement of disease, especially after primary infection. However, the relative amounts of homologous and heterologous anti-E antibodies and their epitopes rem...

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Main Authors: Lai, Chih-Yun, Tsai, Wen-Yang, Lin, Su-Ru, Kao, Chuan-Liang, Hu, Hsien-Ping, King, Chwan-Chuen, Wu, Han-Chung, Chang, Gwong-Jen, Wang, Wei-Kung
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447043/
https://ncbi.nlm.nih.gov/pubmed/18448542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00316-08
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