Analysis of Epitopes on Dengue Virus Envelope Protein Recognized by Monoclonal Antibodies and Polyclonal Human Sera by a High Throughput Assay

BACKGROUND: The envelope (E) protein of dengue virus (DENV) is the major target of neutralizing antibodies and vaccine development. While previous studies on domain III or domain I/II alone have reported several epitopes of monoclonal antibodies (mAbs) against DENV E protein, the possibility of inte...

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Autores principales: Lin, Hong-En, Tsai, Wen-Yang, Liu, I-Ju, Li, Pi-Chun, Liao, Mei-Ying, Tsai, Jih-Jin, Wu, Yi-Chieh, Lai, Chih-Yun, Lu, Chih-Hsuan, Huang, Jyh-Hsiung, Chang, Gwong-Jen, Wu, Han-Chung, Wang, Wei-Kung
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250511/
https://ncbi.nlm.nih.gov/pubmed/22235356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001447
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