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Development of Cell Lines That Provide Tightly Controlled Temporal Translation of the Human Cytomegalovirus IE2 Proteins for Complementation and Functional Analyses of Growth-Impaired and Nonviable IE2 Mutant Viruses

The human cytomegalovirus (HCMV) IE2 86 protein is essential for viral replication. Two other proteins, IE2 60 and IE2 40, which arise from the C-terminal half of IE2 86, are important for later stages of the infection. Functional analyses of IE2 86 in the context of the infection have utilized bact...

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Autores principales: Sanders, Rebecca L., Clark, Charles L., Morello, Christopher S., Spector, Deborah H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446980/
https://ncbi.nlm.nih.gov/pubmed/18463148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00675-08
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