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Synthesis of Genomic and Subgenomic RNA in Mosquito Cells Infected with Two Sindbis Virus nsP4 Mutants: Influence of Intracellular Nucleoside Triphosphate Concentrations

Cells infected with Sindbis virus (SV) make two positive-strand RNAs, a genomic-length RNA (G) RNA and a subgenomic (SG) RNA. In cells infected with SVstd, and in general in cells infected with wt alphaviruses, more SG RNA is made than G RNA. How the balance between synthesis of G RNA and SG RNA is...

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Autori principali: Li, Mei-Ling, Kwan, Tzu-Yu, Simmonds, H. Anne, Stollar, Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446979/
https://ncbi.nlm.nih.gov/pubmed/18508899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00517-08
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